Description
Product Characteristics: CSMD1 CUB and Sushi multiple domains 1 is aproteinthat in humans is encoded by theCSMD1gene. It is a potential tumoursuppressor, the deletion of whicHuman, Mouseay result in head and neckcarcinomasbehaving more aggressively. CSMD1 is part of the complement system that defends against pathogens through either the classical pathway or the alternative pathway. Located primarily in nerve growth cones, CSMD1 blocks the classical pathway of the immune system and is thought to be involved in tumor suppression, as defects in the gene encoding CSMD1 are associated with squamous cell carcinomas.
Target Information: Potential suppressor of squamous cell carcinomas